Gene description for PTPN11
Gene name protein tyrosine phosphatase non-receptor type 11
Gene symbol PTPN11
Other names/aliases BPTP3
CFC
JMML
METCDS
NS1
PTP-1D
PTP2C
SH-PTP2
SH-PTP3
SHP2
Species Homo sapiens
 Experiment description of studies that identified PTPN11 in Retinal pigment epithelial cells

1
Experiment ID2699
Identified moleculeProtein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35333565   
OrganismHomo sapiens
Experiment descriptionLAMP2A regulates the loading of proteins into exosomes
AuthorsFerreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year2022
SampleRetinal pigment epithelial cells
Sample nameARPE-19
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

2
Experiment ID2700
Identified moleculeProtein
Extracellular vesicle typeSmall extracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35333565   
OrganismHomo sapiens
Experiment descriptionLAMP2A regulates the loading of proteins into exosomes
AuthorsFerreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Journal name Sci Adv
Publication year2022
SampleRetinal pigment epithelial cells
Sample nameARPE-19
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

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